Disease: Sezary Syndrome
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNFRSF8 P28908 TNF receptor superfamily member 8 0.86 0.444 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SOCS3 O14543 suppressor of cytokine signaling 3 Enzyme modulator 0.75 0.434 0.808
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
RAG2 P55895 recombination activating 2 2.0E-02 0.507 0.769
PTPN6 P29350 protein tyrosine phosphatase non-receptor type 6 1.00 0.485 0.769
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
NR0B2 Q15466 nuclear receptor subfamily 0 group B member 2 Nuclear receptor 8.3E-06 0.474 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MIR155 microRNA 155 0.384 0.885
JUND P17535 JunD proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.70 0.475 0.808
JUNB P17275 JunB proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.86 0.467 0.769
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
IL5 P05113 interleukin 5 5.7E-03 0.437 0.846
IL22 Q9GZX6 interleukin 22 1.9E-04 0.393 0.885
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IFNG P01579 interferon gamma 0.47 0.288 0.962
FAS P25445 Fas cell surface death receptor 0.81 0.372 0.923
EBI3 Q14213 Epstein-Barr virus induced 3 Signaling 0.11 0.474 0.808
DPP4 P27487 dipeptidyl peptidase 4 Enzyme 7.3E-09 0.420 0.808
CDKN2B P42772 cyclin dependent kinase inhibitor 2B 7.3E-03 0.417 0.769